- Fellowship - Washington University School of Medicine (1998-2000), Neurocritical Care
- Residency - New York University School of Medicine (1995-1998), Neurology
- Internship - The Brooklyn Hospital Center (1994-1995), Internal Medicine
- Residency - National Institute of Mental Health & Neuro Sciences (1987-1992), Neurology
- Medical School - Calcutta Medical College and Hospitals (1980-1986)
Venkatesh Aiyagari, M.D.
Division Chief, Neurocritical Care
- Neurology
- Neuro-Critical Care
Biography
Venkatesh Aiyagari, M.D., is a Professor in the Departments of Neurological Surgery and Neurology at UT Southwestern Medical Center.
A specialist in the neurocritical care of inpatients, Dr. Aiyagari serves as Chief of the Division of Neurocritical Care.
He is certified in neurocritical care by the United Council for Neurologic Subspecialties and in neurology and vascular neurology by the American Board of Psychiatry and Neurology.
Dr. Aiyagari’s research interests include blood pressure management in stroke, quality improvement in neurocritical care, and sodium management in neurological disorders. He has published scores of journal articles, abstracts, and book chapters.
He is a Fellow of the American Heart Association Stroke Council and a Diplomate of the American Board of Psychiatry and Neurology.
Prior to joining the UT Southwestern faculty in 2012, Dr. Aiyagari served as a tenured Associate Professor of neurology and Co-Director of neurocritical care in the Department of Neurology and Rehabilitation at the University of Illinois.
Dr. Aiyagari earned his medical degree at Calcutta Medical College and Hospitals. He completed two neurology residencies, one at the National Institute of Mental Health and Neurosciences, Bangalore, India and another at New York University Medical Center – serving as chief resident his final year – and a fellowship in neurology/neurosurgery intensive care at Washington University School of Medicine.
He serves on the editorial board of Frontiers in Hospitalist Neurology and as an ad hoc reviewer for journals that include JAMA Neurology, Journal of Critical Care, Neurology, Neurocritical Care, Stroke, and Critical Care Medicine.
He is a member of professional organizations that include the American Academy of Neurology, Society of Critical Care Medicine, and Neurocritical Care Society.
Meet Dr. Aiyagari
As a neurocritical care specialist, Venkatesh Aiyagari, M.D., brings together expertise in neurology and critical care medicine – a combination that allows him to provide the best care for people with life-threatening conditions of the brain, spinal cord, and nerves.
“In most intensive care units, the intensivists who care for patients generally don’t have a neurology background, so they don’t have a complete understanding of these diseases,” Dr. Aiyagari says.
Dr. Aiyagari leads UT Southwestern Medical Center’s highly specialized Division of Neurocritical Care, which includes seven physicians all trained in both neurology and critical care. They treat conditions ranging from severe stroke, uncontrolled seizures, and ruptured cerebral aneurysms to acute brain and spinal cord injuries and diseases such as encephalitis, myasthenia gravis, and meningitis.
“We all understand neurological and neurosurgical diseases very well,” he says. “And because we’re also trained in critical care, the care we provide is specifically tailored for ICU patients with disorders involving the brain.”
The Neuroscience Intensive Care Unit at UT Southwestern’s Zale Lipshy Pavilion – William P. Clements Jr. University Hospital is one of the largest facilities of its kind in Texas.
The unit offers a range of state-of-the-art services, including 24-hour video EEG monitoring, end-tidal CO2 monitoring, noninvasive cardiac monitoring, intracranial pressure monitoring, bronchoscopy, and ultrasonography.
“We care for many patients who have been referred by nearby ICU doctors and other physicians who need advanced expertise in neurocritical care that they aren’t equipped to provide,” Dr. Aiyagari says.
Patients receive comprehensive care thanks to the multidisciplinary approach the team employs. Specialists include nurses trained in Neurocritical care, respiratory therapists, a pharmacist, and a dietician, as well as neurosurgeons, occupational and physical therapists, and speech pathologists.
Combining their expertise and experience, Dr. Aiyagari and his colleagues are able to improve the conditions of a number of the critically ill patients they care for.
“Many of our patients who were initially quite sick do get better, and some come back and visit us, walking and talking,” he says. “It’s important to remember that just because someone is in the Neuro ICU it doesn’t mean that he or she can’t improve significantly.”
Education & Training
Honors & Awards
- Lifesaving Partners Award, Gift of Hope (Organ & Tissue Donor Network) 2012
- John S. Garvin MD Teacher of the Year Award, Department of Neurology, University of Illinois at Chicago 2006
Books & Publications
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Books
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Disorders of Consciousness. in Clinical Neurology 2nd ed
Vibhav Bansal, Venkatesh Aiyagari , Sean Ruland (2014), Manson Publishing -
Recurrent Stroke Prevention II: Angiotensin Receptor Blockers (ARBs) ? The LIFE, MOSES and PROFESS Trials. Acute blood pressure management after ischemic stroke in Hypertension and Stroke: Pathophysiology and Treatment
Venkatesh Aiyagari and Philip B Gorelick (2011), New York, Humana Press -
Neurogenic Hypertension including following Stroke and Spinal Cord Injury in Comprehensive Clinical Nephrology
Venkatesh Aiyagari, Sean Ruland and Philip B Gorelick (2010), Mosby
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Disorders of Consciousness. in Clinical Neurology 2nd ed
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Publications
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Quantitative pupillometry in patients with traumatic brain injury and loss of consciousness: A prospective pilot study.
Traylor JI, El Ahmadieh TY, Bedros NM, Al Adli N, Stutzman SE, Venkatachalam AM, Pernik MN, Collum CM, Douglas PM, Aiyagari V, Bagley CA, Olson DM, Aoun SG, Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia 2021 Sep 91 88-92 -
Supratentorial intracerebral hemorrhage volume and other CT variables predict the neurological pupil index.
Mazhar K, Olson DM, Atem FD, Stutzman SE, Moreno J, Venkatachalam A, Aiyagari V, Clinical neurology and neurosurgery 2021 01 200 106410 -
Automated infrared Pupillometer use in assessing the neurological status in pediatric Neurocritical care patients: Case reports and Literature review
Molly E. McGetrick, Nathan Schneider, DaiWai M. Olson, Venkatesh Aiyagari, Darryl Miles Journal of Child Science 2021 11 1 e125-e132 -
Methods for Cleaning and Managing a Nurse-Led Registry.
Venkatachalam AM, Perera A, Stutzman SE, Olson DM, Aiyagari V, Atem FD, The Journal of neuroscience nursing : journal of the American Association of Neuroscience Nurses 2020 Dec 52 6 328-332 -
Automated Pupillometry as a Triage and Assessment Tool in Patients with Traumatic Brain Injury.
El Ahmadieh TY, Bedros NM, Stutzman SE, Nyancho D, Venkatachalam AM, MacAllister M, Ban VS, Dahdaleh NS, Aiyagari V, Figueroa S, White JA, Batjer H, Bagley CA, Olson HDM, Aoun SG, World neurosurgery 2020 Oct -
Early automated infrared pupillometry is superior to auditory brainstem response in predicting neurological outcome after cardiac arrest.
Obinata H, Yokobori S, Shibata Y, Takiguchi T, Nakae R, Igarashi Y, Shigeta K, Matsumoto H, Aiyagari V, Olson DM, Yokota H, Resuscitation 2020 Sep 154 77-84 -
Elevated blood pressure after craniotomy: A prospective observational study.
Perez CA, Stutzman S, Jansen T, Perera A, Jannusch S, Atem F, Aiyagari V, Journal of critical care 2020 Aug 60 235-240 -
Investigation of Pupillary Changes After Carotid Endarterectomy and Carotid Stent Placement Using Automated Pupillometry.
Weerakoon SM, Stutzman SE, Atem FD, Kuchenbecker KS, Olson DM, Aiyagari V, Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association 2020 May 29 5 104693 -
Global Survey of Outcomes of Neurocritical Care Patients: Analysis of the PRINCE Study Part 2.
Venkatasubba Rao CP, Suarez JI, Martin RH, Bauza C, Georgiadis A, Calvillo E, Hemphill JC, Sung G, Oddo M, Taccone FS, LeRoux PD, Neurocritical care 2020 02 32 1 88-103 -
Distributions and Reference Ranges for Automated Pupillometer Values in Neurocritical Care Patients.
Lussier BL, Stutzman SE, Atem F, Venkatachalam AM, Perera AC, Barnes A, Aiyagari V, Olson DM, The Journal of neuroscience nursing : journal of the American Association of Neuroscience Nurses 2019 Dec 51 6 335-340 -
Investigating the association between eye colour and the Neurological Pupil index.
Al-Obaidi S, Atem F, Stutzman SE, Aiyagari V, Olson DM, Australian critical care : official journal of the Confederation of Australian Critical Care Nurses 2019 Nov -
Automated Pupillometry in Neurocritical Care: Research and Practice.
Lussier BL, Olson DM, Aiyagari V, Current neurology and neuroscience reports 2019 Aug 19 10 71 -
Pupillary Light Reflex Variability as a Predictor of Clinical Outcomes in Subarachnoid Hemorrhage.
Ortega-Perez S, Shoyombo I, Aiyagari V, Atem F, Hill M, Stutzman SE, Olson DM, The Journal of neuroscience nursing : journal of the American Association of Neuroscience Nurses 2019 Aug 51 4 171-175 -
Correlation of Objective Pupillometry to Midline Shift in Acute Stroke Patients.
Osman M, Stutzman SE, Atem F, Olson D, Hicks AD, Ortega-Perez S, Aoun SG, Salem A, Aiyagari V, Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association 2019 Jul 28 7 1902-1910 -
An update on neurocritical care for intracerebral hemorrhage.
Reyes R, Viswanathan M, Aiyagari V, Expert review of neurotherapeutics 2019 06 19 6 557-578 -
A Decision Algorithm Is Not Superior to Clinician Judgment to Determine Need for Peripheral vs Central Venous Catheterization.
Panter M, Olson DM, Stutzman SE, Aiyagari V, The Journal of neuroscience nursing : journal of the American Association of Neuroscience Nurses 2019 Jun 51 3 129-133 -
Development and Testing of an Electronic Multidisciplinary Rounding Tool.
Gunter EP, Viswanathan M, Stutzman SE, Olson DM, Aiyagari V, AACN advanced critical care 2019 30 3 222-229 -
Detection of delayed cerebral ischemia using objective pupillometry in patients with aneurysmal subarachnoid hemorrhage.
Aoun SG, Stutzman SE, Vo PN, El Ahmadieh TY, Osman M, Neeley O, Plitt A, Caruso JP, Aiyagari V, Atem F, Welch BG, White JA, Batjer HH, Olson DM Journal of neurosurgery 2019 Jan 1-6 -
Differentiate the Source and Site of Intracranial Pressure Measurements Using More Precise Nomenclature.
Olson DM, Ortega Peréz S, Ramsay J, Venkatasubba Rao CP, Suarez JI, McNett M, Aiyagari V Neurocritical care 2018 Sep -
Understanding the Relationship Between the Neurologic Pupil Index and Constriction Velocity Values.
Shoyombo I, Aiyagari V, Stutzman SE, Atem F, Hill M, Figueroa SA, Miller C, Howard A, Olson DM Scientific reports 2018 May 8 1 6992 -
Correlation of Noninvasive Blood Pressure and Invasive Intra-arterial Blood Pressure in Patients Treated with Vasoactive Medications in a Neurocritical Care Unit.
Saherwala AA, Stutzman SE, Osman M, Kalia J, Figueroa SA, Olson DM, Aiyagari V Neurocritical care 2018 Mar -
"Unwrap the Brain With Rap".
Aiyagari V, Rhines B The Journal of neuroscience nursing : journal of the American Association of Neuroscience Nurses 2018 02 50 1 27-29 -
A Callosal Catastrophe: Toxic Leukoencephalopathy Associated with Thermogenic Weight Loss Supplement Use.
Mahdavi ZK, Narayan R, Mainali S, Greenberg BM, Aiyagari V, McDonagh DL Neurocritical care 2017 Oct -
Establishing Normative Data for Pupillometer Assessment in Neuroscience Intensive Care: The "END-PANIC" Registry.
Olson DM, Stutzman SE, Atem F, Kincaide JD, Ho TT, Carlisle BA, Aiyagari V The Journal of neuroscience nursing : journal of the American Association of Neuroscience Nurses 2017 Aug 49 4 251-254 -
Baseline Hemodynamic Impairment and Future Stroke Risk in Adult Idiopathic Moyamoya Phenomenon: Results of a Prospective Natural History Study.
Derdeyn CP, Zipfel GJ, Zazulia AR, Davis PH, Prabhakaran S, Ivan CS, Aiyagari V, Sagar JR, Hantler N, Shinawi L, Lee JJ, Jafri H, Grubb RL, Miller JP, Dacey RG Stroke 2017 Apr 48 4 894-899 -
Cognitive and Functional Consequence of Cardiac Arrest.
Perez CA, Samudra N, Aiyagari V Current neurology and neuroscience reports 2016 Aug 16 8 70 -
Inter-device reliability of the NPi-100 pupillometer.
Zhao W, Stutzman S, DaiWai O, Saju C, Wilson M, Aiyagari V Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia 2016 Jul -
904: IMPROVING HAND HYGIENE COMPLIANCE IN HOSPITAL CARE.
Liu MA, van de Bruinhorst K, Olson D, Aiyagari V Critical care medicine 2015 Dec 43 12 Suppl 1 227-228 -
The clinical management of acute intracerebral hemorrhage.
Aiyagari V Expert review of neurotherapeutics 2015 Nov 1-12 -
Interrater Reliability of Pupillary Assessments.
Olson DM, Stutzman S, Saju C, Wilson M, Zhao W, Aiyagari V Neurocritical care 2015 Sep -
Cognition and Quality-of-Life Outcomes in the Targeted Temperature Management Trial for Cardiac Arrest.
Aiyagari V, Diringer MN JAMA neurology 2015 Apr -
A Prototype Worldwide Survey of Diagnostic and Treatment Modalities for Stroke.
Aiyagari V, Pandey DK, Testai FD, Grysiewicz RA, Tsiskaridze A, Sacks C, Ogun Y, Ogunrin OA, Uthman BM, Lindsay P, Gorelick PB Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association 2014 Nov -
Emergency and Critical Care Management of Acute Ischaemic Stroke.
Figueroa SA, Zhao W, Aiyagari V CNS drugs 2014 Nov -
The management of hypertension for an acute stroke: what is the blood pressure goal?
Gorelick PB, Aiyagari V Current cardiology reports 2013 Jun 15 6 366 -
Teaching neuroimages: an unusual case of syncope.
Carbunar O, Aiyagari V, Nita DA Neurology 2012 Mar 78 13 e83-4 -
Proof of concept: endogenous antiangiogenic factors predict the occurrence of symptomatic vasospasm post subarachnoid hemorrhage.
Testai FD, Aiyagari V, Hillmann M, Amin-Hanjani S, Dawson G, Gorelick P Neurocritical care 2011 Dec 15 3 416-20 -
Standardized admission and discharge templates to improve documentation of The Joint Commission on Accreditation of Healthcare Organization performance markers.
Whited K, Aiyagari V, Calderon-Arnulphi M, Cursio J, Pandey D, Hillmann M, Ruland S The Journal of neuroscience nursing : journal of the American Association of Neuroscience Nurses 2010 Aug 42 4 225-8 -
Autoregulation after ischaemic stroke.
Powers WJ, Videen TO, Diringer MN, Aiyagari V, Zazulia AR Journal of hypertension 2009 Nov 27 11 2218-22 -
Management of blood pressure for acute and recurrent stroke.
Aiyagari V, Gorelick PB Stroke; a journal of cerebral circulation 2009 Jun 40 6 2251-6 -
Management of hypertension in acute stroke.
Aiyagari V, Badruddin A Expert review of cardiovascular therapy 2009 Jun 7 6 637-46 -
Correction of coagulopathy in warfarin associated cerebral hemorrhage.
Aiyagari V, Testai FD Current opinion in critical care 2009 Apr 15 2 87-92 -
Acute hemorrhagic stroke pathophysiology and medical interventions: blood pressure control, management of anticoagulant-associated brain hemorrhage and general management principles.
Testai FD, Aiyagari V Neurologic clinics 2008 Nov 26 4 963-85, viii-ix -
Cerebrovascular manifestations of pheochromocytoma and the implications of a missed diagnosis.
Majic T, Aiyagari V Neurocritical care 2008 9 3 378-81 -
Fever control and its impact on outcomes: what is the evidence?
Aiyagari V, Diringer MN Journal of the neurological sciences 2007 Oct 261 1-2 39-46 -
Cerebral autoregulation and blood pressure lowering.
Ruland S, Aiyagari V Hypertension 2007 May 49 5 977-8 -
Effect of hyperoxia on cerebral metabolic rate for oxygen measured using positron emission tomography in patients with acute severe head injury.
Diringer MN, Aiyagari V, Zazulia AR, Videen TO, Powers WJ Journal of neurosurgery 2007 Apr 106 4 526-9 -
Counteracting the effects of anticoagulants and antiplatelet agents during neurosurgical emergencies.
Aiyagari V Neurosurgery 2006 Nov 59 5 E1152; author reply E1152 -
Hypernatremia in the neurologic intensive care unit: how high is too high?
Aiyagari V, Deibert E, Diringer MN Journal of critical care 2006 Jun 21 2 163-72 -
Response to discussion by Dr Philip Hebert. Use of recombinant activated factor VIIa (FVIIa) in severe head injury.
Aiyagari V, Diringer MN Journal of critical care 2006 Mar 21 1 115-6; author reply 116 -
Osmolality not predictive of mannitol-induced acute renal insufficiency.
Gondim Fde A, Aiyagari V, Shackleford A, Diringer MN Journal of neurosurgery 2005 Sep 103 3 444-7 -
Effect of normal saline bolus on cerebral blood flow in regions with low baseline flow in patients with vasospasm following subarachnoid hemorrhage.
Jost SC, Diringer MN, Zazulia AR, Videen TO, Aiyagari V, Grubb RL, Powers WJ Journal of neurosurgery 2005 Jul 103 1 25-30 -
Treatment of severe coagulopathy after gunshot injury to the head using recombinant activated factor VII.
Aiyagari V, Menendez JA, Diringer MN Journal of critical care 2005 Jun 20 2 176-9 -
Early mortality following spontaneous intracerebral hemorrhage.
Zurasky JA, Aiyagari V, Zazulia AR, Shackelford A, Diringer MN Neurology 2005 Feb 64 4 725-7 -
Use of recombinant factor VIIa in patients with warfarin-associated intracranial hemorrhage.
Brody DL, Aiyagari V, Shackleford AM, Diringer MN Neurocritical care 2005 2 3 263-7 -
Hourly blood pressure monitoring after intravenous tissue plasminogen activator for ischemic stroke: does everyone need it?
Aiyagari V, Gujjar A, Zazulia AR, Diringer MN Stroke; a journal of cerebral circulation 2004 Oct 35 10 2326-30 -
Untreated subarachnoid hemorrhage: who, why, and when?
Qu F, Aiyagari V, Cross DT, Dacey RG, Diringer MN Journal of neurosurgery 2004 Feb 100 2 244-9 -
CoolGard/Cool Line catheter system.
Aiyagari V, Diringer MN Neurocritical care 2004 1 2 209-11 -
Clinical significance of elevated troponin I levels in patients with nontraumatic subarachnoid hemorrhage.
Deibert E, Barzilai B, Braverman AC, Edwards DF, Aiyagari V, Dacey R, Diringer M Journal of neurosurgery 2003 Apr 98 4 741-6 -
Management of large hemispheric strokes in the neurological intensive care unit.
Aiyagari V, Diringer MN The neurologist 2002 May 8 3 152-62 -
Regional cerebrovascular and metabolic effects of hyperventilation after severe traumatic brain injury.
Diringer MN, Videen TO, Yundt K, Zazulia AR, Aiyagari V, Dacey RG, Grubb RL, Powers WJ Journal of neurosurgery 2002 Jan 96 1 103-8 -
Factors associated with withdrawal of mechanical ventilation in a neurology/neurosurgery intensive care unit.
Diringer MN, Edwards DF, Aiyagari V, Hollingsworth H Critical care medicine 2001 Sep 29 9 1792-7 -
Safety of hemodynamic augmentation in patients treated with Guglielmi detachable coils after acute aneurysmal subarachnoid hemorrhage.
Aiyagari V, Cross DT, Deibert E, Dacey RG, Diringer MN Stroke; a journal of cerebral circulation 2001 Sep 32 9 1994-7 -
Hypoperfusion without ischemia surrounding acute intracerebral hemorrhage.
Zazulia AR, Diringer MN, Videen TO, Adams RE, Yundt K, Aiyagari V, Grubb RL, Powers WJ Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 2001 Jul 21 7 804-10 -
Autoregulation of cerebral blood flow surrounding acute (6 to 22 hours) intracerebral hemorrhage.
Powers WJ, Zazulia AR, Videen TO, Adams RE, Yundt KD, Aiyagari V, Grubb RL, Diringer MN Neurology 2001 Jul 57 1 18-24 -
The failure of neuronal protective agents versus the success of thrombolysis in the treatment of ischemic stroke. The predictive value of animal models.
Jonas S, Aiyagari V, Vieira D, Figueroa M Annals of the New York Academy of Sciences 2001 Jun 939 257-67 -
Reversible left ventricular dysfunction associated with raised troponin I after subarachnoid haemorrhage does not preclude successful heart transplantation.
Deibert E, Aiyagari V, Diringer MN Heart (British Cardiac Society) 2000 Aug 84 2 205-7 -
No reduction in cerebral metabolism as a result of early moderate hyperventilation following severe traumatic brain injury.
Diringer MN, Yundt K, Videen TO, Adams RE, Zazulia AR, Deibert E, Aiyagari V, Dacey RG, Grubb RL, Powers WJ Journal of neurosurgery 2000 Jan 92 1 7-13
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Quantitative pupillometry in patients with traumatic brain injury and loss of consciousness: A prospective pilot study.
Research
- Quality improvement in neurocritical care
- Blood pressure management in stroke
Clinical Focus
- Neuro-Critical Care
Q&A by Dr. Aiyagari
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